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Publications

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Hubert DL, Porter DL, Robinson RD, Mijares ME, Ahmadian E, Arnold KR, Phillips MA. (2026).
Signal, noise, and sampling: How pool size and replication shape metabolomic inference.
G3: Genes|Genomes|Genetics, jkag249.
https://doi.org/10.1093/g3journal/jkag249

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Hubert DL, Bentz EJ, Mason RT. (2026).
Trade-offs between surviving and thriving: A careful balance of physiological limitations and reproductive effort under thermal stress.
Functional Ecology, 40(7), 1994–2010.
https://doi.org/10.1111/1365-2435.70357

Featured on the issue cover https://doi.org/10.1111/1365-2435.70390​

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Katti P, Prasad P, … Hubert DL, et al. (2026).
The MICOS Complex Regulates Mitochondrial Structure and Oxidative Stress During Age-Dependent Structural Deficits in the Kidney.
Aging Cell, 25(5), e70534.
https://doi.org/10.1111/acel.70534

Featured on the issue cover https://doi.org/10.1111/acel.70585

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Hubert DL, Arnold KR, Greenspan ZG, Pupo A, Robinson RD, Chavarin VV, Barter TT, Djukovic D, Raftery D, Vue Z, Hinton AJ, McReynolds MR, Harrison B, Phillips MA. (2025).
Selection for early reproduction leads to accelerated aging and extensive metabolic remodeling in Drosophila melanogaster.
Genome Biology and Evolution, 17(5), evaf082.
https://doi.org/10.1093/gbe/evaf082

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Hubert DL, Bentz EJ, Mason RT. (2024).
Increased offspring size and accelerated gestation in a temperate ectothermic vertebrate under temperatures predicted by a worst-case climate change model.
Journal of Thermal Biology, 125, 103990.
https://doi.org/10.1016/j.jtherbio.2024.103990

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Hewitt KM, Kayes LJ, Hubert DL, Chouinard A. (2014).
Investigating issues in the laboratory: The behavior of red swamp crayfish as an invasive species.
The American Biology Teacher, 76(9), 609–614.
https://doi.org/10.1525/abt.2014.76.9.7

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Manuscripts and Preprints

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Hubert DL, Bentz EJ, Mason RT. (2026).
Cold, dark, and hungry: Dynamic transcriptional regulation across eight months of brumation.
Under review, Journal of Experimental Biology.
Preprint: https://doi.org/10.64898/2026.06.11.731677

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Hinton AO, Masenga SK, … Hubert DL, et al. (2026).
Nutrient State, Aging, and Diet Modulate SAM50-Dependent Mitochondrial Remodeling and Systemic Metabolic Signatures.
Under review, npj Metabolic Health and Disease.
Preprint: https://doi.org/10.21203/rs.3.rs-8704245/v1

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Vue Z, Ajayi P, Neikirk K, … Hubert DL, et al. (2026).
Human Heart Failure Alters Mitochondria and Myofibril 3D Structure Triggering Metabolic Shifts.
Under review, Circulation Research.
Preprint: https://doi.org/10.1101/2023.11.28.569095

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Shao B, Kula B, … Hubert DL, et al. (2025).
The role of MICOS in modulating mitochondrial dynamics and structural changes in vulnerable regions of Alzheimer’s Disease.
Under review, Nature Neuroscience.
Preprint: https://doi.org/10.64898/2025.12.13.693635

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Masenga SK, Murphey A, … Hubert DL, et al. (2025).
Age-related MICOS Complex Dysregulation Impairs Mitochondrial 3D Architecture and Metabolic Homeostasis in the Liver.
Under review, Aging Cell.
Preprint: https://doi.org/10.1101/2024.06.20.599846

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Wanjalla C, Obare L, Bailin S, … Hubert DL, et al. (2024).
HIV persists in late coronary atheroma and is associated with increased local inflammation and disease progression.
Under review, Nature Communications.
Preprint: https://doi.org/10.21203/rs.3.rs-5125826/v1

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©2026 by David L. Hubert

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